Project Name: Research Package Report Generator

Sponsor:
Michael Van Gilder (email: uphill@cox.net)
Michael Neely (email: mneely@usc.edu)
Roger Jelliffe (email: jelliffe@usc.edu)

Partners:
None

Background:
The objective of the USC Laboratory of Applied Pharmacokinetics (LAPK) is to create population models of drug behavior, and to apply these models by precisely tailoring patients’ dosage regimens. Researchers build population pharmacokinetic (PK) and pharmacodynamic (PD) models. Clinicians use a modified version of the same model to assist them in getting a particular drug concentration in a patient’s body.

Problem:
The USC*PACK research package output is a PD/PK model built by a researcher. These models are multidimensional and therefore difficult to visualize. Similar data is plotted in the clinical package with the help of two COTS projects, but different ways of representing the data are needed. Stingray, by Dazdaq is one of the COTS products and the other is ProEssentials, by Gigasoft.

Constraints:
The PD/PK model should be saved so that it may be used later. A COTS package is preferable. The proposed system should be able to interface and work with existing software.

Desired Deliverables:
A tool that displays and generates reports (graphs/plots) for multidimensional PK/PD models or modification and additions to the currently used software tools, Stingray and Pro-Essentials, is desired. The resulting graphs/plots should be in a printer-friendly format.